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| Identification of Shikonin and Its Derivatives from Lithospermum erythrorhizon |
| Jin⁃Sook Kim1, Young⁃Sil Han2 and Myung⁃Hwa Kang3 |
| 1National Rural Resources Development Institute, RDA, Suwon 441-853, Korea; 2Dept. of Food and Nutrition, Sookmyung Women's University, Seoul 140-742, Korea; 3Dept. of Food Science and Nutrition, Hoseo University, Asan 336-795, Korea |
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Abstract
| In this study, phytochemicals from the wold and cultivated Lithospermum erythrorhizon (gromwell), which has been used for medicinal purpose or natural coloring material from the old days, were extracted by methanol and fractionated with hexane. The shikonin compounds in the fraction was isolated and their chemical structures were identified by 1H and 13C⁃NMR. It was found that compound I was the shikonin substance with molecular weight of 288.3 and chemical formula of C16H16O5, and compound Ⅱ being deoxyshikonin substance with molecular weight of 272.3 and chemical formula of C16H16O4. The quantities of these compounds in the wild and cultivated gromwells was determined. |
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| Key words : Lithospermum erythrorhizon:gromwell:shikonin:identification |
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| Journal of the Korean Society of Food Science and Nutrition 35(2), 177~181 (2006) |
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